The incident occurred in Dutchess County around 3:40 p.m., Wednesday, July 17, on Route 9 near Rochambeau Lane in the town of Poughkeepsie.
According to Capt. Michael O'Dowd of the town of Poughkeepsie Police said a 2017 Chevrolet sedan driven by a Poughkeepsie man made a left turn from the southbound side of South Road into the northbound side of South Road.
O'Dowd said that the Chevrolet collided with a 2017 Hyundai hatchback driven by a Poughkeepsie woman traveling north during the turn.
The woman received serious physical injuries and was transported to a hospital.
The roadway was closed for several hours following the crash.
The investigation is ongoing, and police ask any witnesses to contact the Traffic Division at 845-790-4686.
This is a developing story. Check back to Daily Voice for updates.
Click here to follow Daily Voice Highlands and receive free news updates.